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Neutrons

This tag is associated with 3 posts

Bundeswehr Medical Service Writes About DFPase

The Bundeswehr Medical Service (Sanitätsdienst der Bundeswehr) writes about DFPase and our neutron structure on its web page. The article (in German) can be found here.

Neutron Structure of the Enzyme DFPase

A new publication in the journal Proceedings of the National Academy of Sciences of the USA (PNAS) describes the neutron diffraction structure of the enzyme DFPase. Neutron diffraction allows the visualization of hydrogen atoms in protein structures and thus the determination of protonation states and orientations of solvent water molecules. The results of the study confirm the proposed reaction mechanism for DFPase and permit the directed introduction of modifications to the enzyme by mutagenesis to enhance both turnover rates and substrate diversity.

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